Coffee in Increased Risk of Lung Cancer Linearly

Bad news for coffee lovers, the recent study suggested that regular coffee consumption tin may associate to increased risk of lung cancer.

Coffee, a popular and social beverage all over the world, particularly in the West, is a drink made from roast bean from the Coffea plant, native to tropical Africa and Madagascar.

Lung cancer is a medical condition caused by irregular cell growth in the lung. At the later stage, cancer cells may spread to distant tissues and organs.

Dr. Wang Y, the lead author said, "a linear dose-response relationship exists between coffee consumption and risk of lung cancer".


In the clarified risk of coffee in induced lung cancer, the Shanghai Institute of Pharmaceutical Industry conducted a search in the database of PubMed and Embase, from 1966 to January 2009. In 5 prospective studies and 8 case-control studies involving 5347 lung cancer cases and 104,911 non-cases selected, researchers found that
1. The coffee high amount of intake was associated to a significant positive lung cancer risk
2. Risk of lung cancer increased by 14% for additional 2 cups consumed daily.

Interestingly, prospective studies conducted in America and Japan showed a significantly associated with increased risk of lung cancer in highest coffee consumption, but borderline significantly associated with decreased risk of lung cancer in non-smokers in compared to studies conducted from other countries.

And people drinking decaffeinate coffee showed a decreased risk of lung cancer in all studies.

Other, in the review of seventeen studies (5 cohort and 12 case-control studies) involving 12 276 cases and 102 516 controls met the predetermined inclusion criterion, extracted from the database of literature, the total risk of coffee intake and lung cancer incidence was 1.17 in compared to nondrinkers. Also in compared to nondrinkers, the relative risk of lung cancer was associated with numbers of a cup per day consumed,
1. 1.10 (95% CI: 0.92-1.31) for ⩽1 cup per day,
2. 1.10 (95% CI: 0.93-1.30) for 2-3 cups per day and
3. 1.20 (95% CI: 1.02-1.39) for ⩾3 cups per day.


More importantly, Dr. Xie Y, the lead author said, " Significant associations for high coffee intake with increased risk of lung cancer were observed in men (OR=1.41 95% CI: 1.21-1.63), but not in women (OR=1.16, 95% CI: 0.86-1.56), in American (OR=1.34 95% CI: 1.08-1.65) and Asian populations (OR=1.49 95% CI: 1.28-1.74), but not in European populations (OR=1.12, 95% CI: 0.74-1.67), and in smokers (OR=1.24, 95% CI: 1.00-1.54), but not in nonsmokers (OR=0.85, 95% CI: 0.64-1.11)".

Taking all together, there is no doubt that regular coffee intakes of large amounts is associated linearly in an increased risk of lung cancer, particularly in men and smokers.


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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Coffee and tea consumption and risk of lung cancer: a dose-response analysis of observational studies by Wang Y, Yu X, Wu Y, Zhang D.(PubMed)
(2) Coffee consumption and risk of lung cancer: a meta-analysis by Tang N1, Wu Y, Ma J, Wang B, Yu R.(PubMed)