The Fabulous Smoothie of Ginger, Turmeric and Tomatoes for Prevention and Treatment of Premenstrual syndrome(PMS)

Kyle J. Norton(Scholar and Master of Nutrients) all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment women with premenstrual syndrome
Yield: 2 serving (about 8 ounce each)
1 1/2 cups tomatoes
1 large slice of ginger
1 tsp of curcumin
1 cup of rice milk


1. Place the tangerines, carrot and green tea, in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

The finding the natural ingredient for prevention and treatment of premenstrual syndrome to replace the adverse effects of conventional medicine has been facing many obstacles. Many initially potentially therapeutic values working in animal studies does not produce the same effectiveness in human trials.

Scientists in some well known institution may have found the combination of ingredients of ginger(1), curcumin(3) and tomatoes(7) with therapeutic values for reduced painful symptoms and treatment of premenstrual syndrome, recent studies suggested.

Premenstrual syndrome effects over 70% to 90% of women in the US and less for women in Southeast Asia because of their difference in living style and social structure. It is defined as faulty function of the ovaries related to the women's menstrual cycle, it effects a women's physical and emotional state, and sometimes interferes with daily activities as a result of hormone fluctuation. The syndrome occurs one to two weeks before menstruation and then declines when the period starts.

Ginger (Zingiber officinale) or ginger root is the genus Zingiber, belongings to the family Zingiberaceae, native to Tamil, used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
The use of ginger for treatment of pain, including PMS may be resulted of its anti-inflammatory constituents, according to the review of data base of studies(2).According to the joint study lead by the Zahedan University of Medical Sciences, in a a clinical trial, double-blinded work, and participants randomly allocated, intake of 2 ginger capsules daily from seven days before menstruation to three days after menstruation for three cycles, significantly reduced severity of the symptoms by daily record scale in woman with PMS(1).

Turmeric is a perennial plant in the genus Curcuma, belongings to the family Zingiberaceae, native to tropical South Asia, used in trditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc. Its phytochemical curcumin has showed to exhibit anti PMS effect, through mediating enhancing serum BDNF levels, a biological marker for depressive state(3)In a a clinical trial, double-blinded study of women suffering from PMS, through modulation of neurotransmitters and anti-inflammatory effects, curcumin attenuated severity of PMS symptoms such as improvement of psychological, physical and behavioral changes(4).

Tomato is a red, edible fruit, genus Solanum, belongs to family Solanaceae, native to South America. Because of its health benefits, tomato is grown world wide for commercial purpose
and often in green house. its steroidal glycosides isolated from the ripe fruit of the cherry tomato(6) was found effectively in treatment of symptoms of PMS in women through the effect of metabolization of steroidal hormone in exhibiting various physiological activities(5).
Carotenoids, another major constituent found in tomato, may also associate with symptoms of premenstrual syndrome (PMS). According to the University of Texas Medical Branch, women with PMS have hound to strongly related to deficiency of vitamin A(7).

Dietary supplement "Karinat" which contains beta-carotene 2.5 mg, alpha-tocopherol 5 mg, ascorbic acid 30 mg and garlic powder 150 mg per one tablet, effectively reduced the severity of mastalgia, premenstrual syndrome, dysmenorrhea and algomenorrhea and caused regression of palpable symptoms of the breast fibromatosis, according to Dr. Bespalov VG, and colleagies(8).

Taking altogether, women who are at increased risk of PMS due to menstrual irregularity .....should drink at least one serving daily and women with PMS should drink the smoothie as much as they can, depending to digestive toleration.
Change life style and diet pattern are also recommended.

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References
(1) Effect of treatment with ginger on the severity of premenstrual syndrome symptoms by Khayat S1, Kheirkhah M2, Behboodi Moghadam Z3, Fanaei H4, Kasaeian A5, Javadimehr M6.(PubMed)
(2) The use of ginger (Zingiber officinale) for the treatment of pain: a systematic review of clinical trials by Terry R1, Posadzki P, Watson LK, Ernst E.(PubMed)
(3) Effect of curcumin on serum brain-derived neurotrophic factor levels in women with premenstrual syndrome: A randomized, double-blind, placebo-controlled trial by Fanaei H1, Khayat S2, Kasaeian A3, Javadimehr M4.(PubMed)
(4) Curcumin attenuates severity of premenstrual syndrome symptoms: A randomized, double-blind, placebo-controlled trial by Khayat S1, Fanaei H2, Kheirkhah M3, Moghadam ZB4, Kasaeian A5, Javadimehr M6.(PubMed)
(5) Metabolism of tomato steroidal glycosides in humans by Noguchi E1, Fujiwara Y, Matsushita S, Ikeda T, Ono M, Nohara T.(PubMed)
(6) A new steroidal glycoside and a new phenyl glycoside from a ripe cherry tomato by Ono M1, Shiono Y, Yanai Y, Fujiwara Y, Ikeda T, Nohara T.(PubMed)
(7) Vitamin A levels in premenstrual syndrome by Chuong CJ1, Dawson EB, Smith ER.(PubMed)
(8) [Study of an antioxidant dietary supplement "Karinat" in patients with benign breast disease].[Article in Russian] by Bespalov VG, Barash NIu, Ivanova OA, Krzhivitskiĭ PI, Semiglazov VF, Aleksandrov VA, Sobenin NA, Orekhov AN.(PubMed)