All About Vitamins: niacin in Prevented Migraine Caused by Low Level of Serotonin

By Kyle J. Norton.

Niacin, is also known as vitamin B3, nicotinic acid, an organic compound with the formula
C6H5NO2, found abundantly in chicken, beef, fish, cereal, peanuts and legumes. It is best known for its effects in lowering cholesterol and triglycerides and removing toxic from our body and promoting production of steroid hormones.

Niacin may be one of the B vitamin with a substantial effect in migraine prevention, a renowned institute study suggested.

According to the Division of Pain Management Mayo Clinic, niacin showed to increase plasma serotonin levels in reduced migraine expression at the early stage.

Sustained-release niacin merits may be important to provide a potentially useful preventive therapy for migraine headache. Dr. Velling DA, the lead authors insisted.

Furthermore, in the review of literature in English and non-English language articles of the databases: MEDLINE (1966-February 2004), AMED (1995-February 2004) and Alt HealthWatch (1990-February 2004),  9 articles met the inclusion criteria included in this systematic analysis showed a moderated effect of niacin in prevented migraines and tension-type headaches not only through its vasodilatory properties but also improved mitochondrial energy metabolism.

Unfortunately, although adverse effects are well tolerated, some patients experience serve flushing, nausea and fainting.

Dr. Prousky J, the lead researcher said. "Although niacin's mechanisms of action have not been substantiated from controlled clinical trials, this agent may have beneficial effects upon migraine and tension-type headaches. Adequately designed randomized trials are required to determine its clinical implications".

Taking together, as a supplement, niacin may be effective in prevented migraine caused by low level of serotonin..

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Sources
(1) Sustained-release niacin for prevention of migraine headache by Velling DA1, Dodick DW, Muir JJ.(PubMed)
(2) The treatment of migraines and tension-type headaches with intravenous and oral niacin(nicotinic acid): systematic review of the literature by Prousky J1, Seely D.(PubMed)


Biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.