All About Vitamins: Niacin Overdoses and The Risk of Toxicity

By Kyle J. Norton.

Niacin, is also known as vitamin B3, nicotinic acid, an organic compound with the formula
C6H5NO2, found abundantly in chicken, beef, fish, cereal, peanuts and legumes. It is best known for its effects in lowering cholesterol and triglycerides and removing toxic from our body and promoting production of steroid hormones.

Niacin may induce liver toxicity if over dose, a joint study lead by the Mayo Clinic insisted.

In a analysis of a A 17-year-old male was transferred to the pediatric intensive care unit for evaluation of acute liver failure, researchers found that elevated liver transaminases induced acute liver toxicity caused by over dose of niacin intake to alter the outcome of an upcoming drug test.

Due to the severity of the case, Dr. Ellsworth MA, the lead author said, "Pediatric providers should be aware of the risks associated with niacin toxicity and other experimental medical therapies that may be described on the Internet or other nonreputable ".

Other in the differentiation of a 23-year-old healthy man presented to an Emergency Department with altered mental status, fever, acute renal failure, microangiopathic hemolytic anemia, thrombocytopenia, and coagulopathy,doctors at the Carolinas Medical Center, found that respiratory failure and hemodialysis for acute renal failure were caused by intake of 22.5 g of sustained-release niacin over the preceding 48 h with an attempt to pass a pre-employment urine drug screen.

Dr, Daul AM, the lead researcher warmed, " Although this patient was fortunate to make a full recovery, the case highlights the potential for multi-system toxicity with niacin overdose, and the potential for harm posed by medical misinformation on the Internet".

Taking altogether, overdoses of niacin may cause significant damage to your health in exhibited long term liver and kidney damage if not treated immediately.

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Sources


Biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Acute liver failure secondary to niacin toxicity by Ellsworth MA1, Anderson KR2, Hall DJ2, Freese DK3, Lloyd RM4.(PubMed)
(2) Niacin toxicity resulting from urine drug test evasion by Daul AM1, Beuhler MC.(PubMed)