All About Vitamins: Niacin in reduced Risk Oxidative Stress

By Kyle J. Norton.

Niacin, is also known as vitamin B3, nicotinic acid, an organic compound with the formula
C6H5NO2, found abundantly in chicken, beef, fish, cereal, peanuts and legumes. It is best known for its effects in lowering cholesterol and triglycerides and removing toxic from our body and promoting production of steroid hormones.

Niacin may be considered as dietary supplement in reduced risk of oxidative stress in induction of various diseases, a respectable institute study opinionated.

In a total of 127 men and women aged 48-77 yr with brachial artery flow-mediated dilation (FMD), patients, above-average dietary niacin intake showed a significant greater function in compared to those below-average intake (P < 0.05).

The study also found that above-average dietary niacin intake patients showed a lower levels of oxidative stress through expression of plasma oxidized low-density lipoprotein.

Further more, levels of antioxidants also has linearly association to amount intake of niacin as shown in this participants.

Dr. Kaplon RE, the lead author said, " higher dietary niacin intake is associated with greater vascular endothelial function related to lower systemic and vascular oxidative stress among healthy middle-aged and older adults."

In support of the above analysis, the study of 17 patients with hypercholesterolemia and low HDL-C and 8 healthy control subjects, 12 weeks.of niacin treatment showed a strong improvement of lipid profile, oxidative stress and C-reactive protein (CRP) levels, through increase in HDL-C and apolipoprotein A1 levels involving transferred to HDL in the bloodstream and a decrease in triglyceride levels.

More promisingly, Niacin treatment in these patients with low HDL levels showed a significant in reduced oxidative stress through improved activities in regulated C-reactive protein (CRP) levels and lipid profiles.

Taking altogether, There is no doubt that niacin may be considered as a dietary treatment in reduced risk of diseases caused by oxidative stress.

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Sources
(1) Vascular endothelial function and oxidative stress are related to dietary niacin intake among healthy middle-aged and older adults by Kaplon RE1, Gano LB, Seals DR.(PubMed)

(2) Niacin administration significantly reduces oxidative stress in patients with hypercholesterolemia and low levels of high-density lipoprotein cholesterol by Hamoud S1, Kaplan M, Meilin E, Hassan A, Torgovicky R, Cohen R, Hayek T.(PubMed)

Biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.