All About Vitamins: Niacin Reduced Risk and Treatment Glaucoma?

By Kyle J. Norton.

Niacin, is also known as vitamin B3, nicotinic acid, an organic compound with the formula
C6H5NO2, found abundantly in chicken, beef, fish, cereal, peanuts and legumes. It is best known for its effects in lowering cholesterol and triglycerides and removing toxic from our body and promoting production of steroid hormones.

Niacin supplement may have a potential effect in reduced risk and treatment glaucoma, a Pennsylvania study suggested.

Intake of 500 mg of oral niacin(also known as vitamin B3 or nicotinic acid) daily is shown to increased intraocular pressure to 37 and 27 mm Hg, according to the the Jefferson Medical College. study.

In the exam of 73-year-old man with a history of primary open-angle glaucoma, intake of niacin have a significant effect on the eye pressure which may be increased or decreased depending to amount of niacin intake.

The increased abnormal eye pressure also reduced to normal once niacin intake was stopped.

The finding is contrasted to the investigation of mice treated with nicotinamide adenine dinucleotide (NAD), in genetically predisposed to developing glaucoma with healthy mice acted as control, in indication of niacin effect in treatment of glaucoma through anti oxidative stress by Dr. John and colleagues. 

According to Dr. John and colleagues study, the depletion of NAD weakens the metabolism of the brain cells, and intraocular pressure may have a direct influence on the onset of glaucoma. And  in glaucoma-predisposed mice, adding niacin to the drinking water showed to improve aging retinal ganglion cells and modify the neuro change associated with advancing age and prevent the early onset of glaucoma.

Taking altogether, intake of niacin supplement to reduced risk and treatment of glaucoma may need further studies by larger human trial and involvement of multi centers before confirming.

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Sources
(1) Oral niacin can increase intraocular pressure by Tittler EH1, de Barros DS, Navarro JB, Freitas DG, Gheith ME, Siam GA, Spaeth GL.(PubMed)
(2) http://dailyhealthalerts.com/new-study-vitamin-b3-may-help-glaucoma-and-macular-degeneration/
(3) Vitamin B-3 successfully prevents glaucoma in mice by By Ana Sandoiu
Published Friday 17 February 2017(Medical News Today)

Biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.