The Smoothie of Green tea and Blueberry for Prevention and treatment of Renal infection in Autosomal recessive polycystic kidney disease

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.

Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.

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The smoothie for prevention and treatment of Renal infection Autosomal recessive polycystic kidney disease

Yield: 2 servings (about 8 ounces each)

1 1/2 Blueberry
1 cup green tea drink (Make from 4 grams of green tea, a slice of ginger and a cup of hot water lipped for 5 minutes, and let cool to room temperature)

1. Place all ingredients in a blender and puree about 1 minute

2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.

3. Serve immediately

The finding of a natural source for treatment of Autosomal recessive polycystic kidney disease has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Autosomal recessive polycystic kidney disease is an inherited diseases(Mutations in the PKHD1)causing abnormal functions of liver and kidney inducing morbidity and mortality in children.

Until today, there is no cure, treatment options for autosomal recessive polycystic kidney disease, depending to complications such as infection.

Renal infection is a specific type of progression of infection involved to involve the upper urinary system, including the kidneys and ureters.

Recent studies back by well known institutions proposed, Green tea, Olive and Blueberry may be the next generation of natural ingredients for prevention and treatment of Reno infection in Autosomal recessive polycystic kidney disease.

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects. According to the Shanghai Ocean University, (-)-epigallocatechin-3-gallate uisolated from green tea expressed strong anti Grass carp reovirus effect in a dose-dependent manner(1). As the virus has shown to induce apoptosis and oxidative stress in grass carp (Ctenopharyngodon idellus) kidney cell line(2).

Green tea extract, in fact also protected and maintained renal function during malaria infection, through inhibition of oxidative stress as well as decreased significantly the blood urea nitrogen and creatinine levels in plasma(3). 

Furthermore, the extract ameliorated Gentamicin (GM), an effective antibiotic against severe infection, induced nephrotoxicity and oxidative damage by improving antioxidant defense and tissue integrity(4).

Resveratrol, a phytochemical in the class of Stilbenoids, found abundantly in grape and blueberry may also be benefits for treatment of reno infection by by suppressing inflammation driven by macrophages(5). According to the Nanjing Medical University, resveratrol protected against renal infection through attenuated aldosterone-induced mitochondrial malfunction and podocyte injury in aldosterone-infused mice(6).

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references

(1) Identification of (-)-epigallocatechin-3-gallate as a potential agent for blocking infection by grass carp reovirus by Wang H1, Liu W1, Yu F1, Lu L2.(PubMed)

(2) Grass carp reovirus induces apoptosis and oxidative stress in grass carp (Ctenopharyngodon idellus) kidney cell line by Jia R1, Cao LP2, Du JL2, Liu YJ3, Wang JH3, Jeney G4, Yin GJ5.(PubMed)

(3) Protection of renal function by green tea extract during Plasmodium berghei infection by Somsak V1, Jaihan U, Srichairatanakool S, Uthaipibull C.(PubMed)

(4) Amelioration of gentamicin nephrotoxicity by green tea extract in uninephrectomized rats as a model of progressive renal failure by Salem EA1, Salem NA, Kamel M, Maarouf AM, Bissada NK, Hellstrom WJ, Eladl M.(PubMed)

(5) Resveratrol attenuates lipopolysaccharide-induced acute kidney injury by suppressing inflammation driven by macrophages by Chen L1, Yang S, Zumbrun EE, Guan H, Nagarkatti PS, Nagarkatti M.(PubMed)

(6) Activation of peroxisome proliferator-activated receptor-γ coactivator 1α ameliorates mitochondrial dysfunction and protects podocytes from aldosterone-induced injury by Yuan Y1, Huang S, Wang W, Wang Y, Zhang P, Zhu C, Ding G, Liu B, Yang T, Zhang A.(PubMed)