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The smoothie for reduced risk and Treatment of Cirrhosis
Yield: 2 servings (about 8 ounces each)
1 cup tomato
1/2 cup grape
1 cup green tea drink (Make from 4 grams of green tea, and a cup of hot water lipped for 5 minutes. Set aside for cooling to room temperature)
1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately
The finding the natural ingredients for treatment of Cirrhosis considered as a dream of many scientist to replace the long usage adverse effect of conventional medicine . Unfortunately, many compounds found effective in initial studying failed to confirm the potential in large sample size and multi center.
Cirrhosis is a condition of irreversible scarring liver as a result of liver tissue by fibrosis due to final phase of chronic liver diseases of that can lead to poor function of the liver and liver failure. According to the statistics, Number of discharges with chronic liver disease or cirrhosis as the first-listed diagnosis: 101,000 in 2009 and Deaths per 100,000 population: 10.3 in 2010(1). Hepatitis B infection cause of the disease is very prevalent in South-East Asia.
Naringenin, an phytochemical found in Citrus fruits, including orange attenuated the expression of liver fibrosis by exhibiting antioxidant and anti-inflammatory activities(5).
Flavonoids, a group of plant phytochemicals found abundantly in apple may consist a numbers of health benefit through its effects in cell signalling pathways and antioxidant activity. According to the Chinese study, flavonoids, attenuate the risk of thioacetamide-induced hepatic fibrosis through mechanism related to the down-regulation of the protein expressions of TGF-β1 in controlling the expression of proliferation, differentiation, and Caspase-3 in cell apoptosis(8).
The phytochemical , flavonoids found in the the extracts of pomegranate peels (EPP) and seeds (EPS) also exerted the protective effects against liver fibrosis induced by CCl4, through restored the decreased superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) activities and inhibited the formation of lipid peroxidized products(9).
Dr. Yuan LP and colleagues at the College of Pharmacy, Anhui Medical University said,"(the) total flavonoids of Bidens bipinnata L.b was able to ameliorate liver injury and protect rats from CCl4-induced liver fibrosisby suppressing oxidative stress" through " inhibiting the induction of NF-kappaB (proinflammatory signaling pathway) on hepatic stellate cell activation and the expression of TGF-beta1 in controlling cells proliferation, differentiation"(10).
The combined ingredient found in green tea, orange and apple may contribute to further investigation of therapeutic natural ingredients for reduced risk and treatment of Cirrhosis .
People who are at increased risk of Cirrhosis due to family history, genetic mutation,... should drink at least one serving daily and people with Cirrhosis should drink as much as they can, depending to digestive toleration.
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